The role of calbindin-D28k on renal calcium and magnesium handling during treatment with loop and thiazide diuretics
نویسندگان
چکیده
Chien-Te Lee, Hwee-Yeong Ng, Yueh-Ting Lee, Li-Wen Lai, and X Yeong-Hau H. Lien Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang-Gung Memorial Hospital, Kaohsiung, Taiwan, and Chang-Gung University, College of Medicine, Taoyuan, Taiwan; Kidney Research Center, Chang Gung Memorial Hospital, Chang-Gung University, College of Medicine, Taoyuan, Taiwan; Departments of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona; Arizona Kidney Disease and Heart Center, Tucson, Arizona; and Department of Medicine, University of Arizona, Tucson, Arizona
منابع مشابه
Re: The Role of Calbindin-D28k on Renal Calcium and Magnesium Handling during Treatment with Loop and Thiazide Diuretics.
Calbindin-D28k (CBD-28k) is a calcium binding protein located in the distal convoluted tubule (DCT) and plays an important role in active calcium transport in the kidney. Loop and thiazide diuretics affect renal Ca and Mg handling: both cause Mg wasting, but have opposite effects on Ca excretion as loop diuretics increase, but thiazides decrease, Ca excretion. To understand the role of CBD-28k ...
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